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antagonist

American  
[an-tag-uh-nist] / ænˈtæg ə nɪst /

noun

  1. a person who is opposed to, struggles against, or competes with another; opponent; adversary.

    Synonyms:
    foe, enemy, contestant
    Antonyms:
    friend, ally
  2. the adversary of the hero or protagonist of a drama or other literary work.

    Iago is the antagonist of Othello.

  3. Physiology. a muscle that acts in opposition to another.

  4. Dentistry. a tooth in one jaw that articulates during mastication or occlusion with a tooth in the opposing jaw.

  5. Pharmacology. a drug that counteracts the effects of another drug.


antagonist British  
/ ænˈtæɡənɪst /

noun

  1. an opponent or adversary, as in a contest, drama, sporting event, etc

  2. any muscle that opposes the action of another Compare agonist

  3. a drug that counteracts the effects of another drug Compare synergist

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

antagonist Scientific  
/ ăn-tăgə-nĭst /
  1. A muscle that opposes the action of another muscle, as by relaxing while the other one contracts, thereby producing smooth, coordinated movement.

  2. A chemical substance, such as a drug, that interferes with the physiological action of another substance, especially by combining with and blocking its nerve receptor.

  3. Compare agonist


Related Words

See adversary.

Etymology

Origin of antagonist

First recorded in 1590–1600; from Late Latin antagōnista, from Greek antagōnistḗs. See antagonize, -ist

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Mr. Ireland sketches the antagonists with vivid details.

From The Wall Street Journal

And he had a running feud with Earl Weaver since the two, an unmoored umpire and a fiery manager, were antagonists in the Double-A Eastern League.

From The Wall Street Journal

Mays and Clemmett are well matched as antagonists, balancing the flamboyant flaws and stubborn humanity of their characters.

From Los Angeles Times

The vampire Remmick is more than just an antagonist with fangs.

From Los Angeles Times

But Messrs. Smith and Delich make for persuasive antagonists, even if one does want to point out, as they wrangle, that there are bigger things around to be concerned about.

From The Wall Street Journal