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sickle cell

American  

noun

Pathology.
  1. an abnormal red blood cell having an elongated, crescentlike shape due to the presence of an abnormal hemoglobin.


Etymology

Origin of sickle cell

First recorded in 1925–30; so called from the fact that the cells are often sickle-shaped

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

People living with sickle cell disease have red blood cells that are crescent shaped due to a gene mutation.

From Los Angeles Times

While making the project, his mother suffered two strokes, his brother was treated for psychosis, and his younger sister died of sickle cell anaemia.

From BBC

"The first gene editing drug approved for a blood disease -- sickle cell anemia -- targets a cell-type specific enhancer."

From Science Daily

Cases include electrocution, drowning, overdose, scurvy, sickle cell anemia, a nail in the chest, a fastball in the eye and gallstones, with all the personal drama one expects from a hospital show.

From Los Angeles Times

The biotech said a Phase 3 trial for mitapivat, a drug to treat sickle cell disease, had failed to meet several endpoints.

From Barron's